PathologybioRxivPreprint
CD239 deficiency in distal tubules impairs cell polarity and increases susceptibility to renal injury
DOI 10.64898/2026.05.31.728029
Author
National Institute of Global Health and MedicineORCID 0000-0003-2500-7973Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Nam Chul Kim, Minoru Tanaka, Isabelle Draper…·Atsushi Asakura
This study investigates JAG2-related muscular dystrophy by examining the role of Notch signaling in muscle stem cells, finding that JAG2 variants disrupt both autocrine and paracrine Notch signaling, impairing muscle regeneration.