Cyntia Tremblay

This study shows that introducing natural microbial environments to mice alters microglial states and transcriptional programs, increasing similarity to human Alzheimer's disease profiles.

This study finds higher ACE2 levels in the brains of Alzheimer's patients, which may increase CNS SARS-CoV-2 infection risk.

The paper shows that insulin receptors in microvessels at the blood-brain barrier are defective in Alzheimer's disease, contributing to brain insulin resistance and cognitive impairment.

This study shows that CD2AP loss in brain endothelial cells impairs vascular function and memory in AD models, suggesting therapeutic targeting of CD2AP pathways.