Cell BiologybioRxivPreprint
V-ATPase-Driven Lysosomal Activation Orchestrates MEK2-Induced Endothelial Reprogramming
Ziad Sabry, Max Keller, Liu Liu…·Zhong Wang
This paper shows that MEK2 activation reprograms fibroblasts into endothelial-like cells by enhancing lysosomal activity through the V-ATPase-TFEB axis.
DOI 10.64898/2026.06.09.731136