Brice Chanez

This paper evaluates transcriptomic FOLFIRINOX sensitivity signatures in neoadjuvant pancreatic cancer, finding they predict survival and show directional reclassification after treatment.

The paper shows that GALA, a process relocating GALNTs to the ER, enables co-translational O-glycosylation in pancreatic cancer, expanding the O-glycoproteome and promoting tumor growth.

The paper identifies PTK7 as a marker for colorectal cancer cell plasticity and metastatic potential, showing its loss in circulating tumor cells enables stress resistance and metastasis through surfaceome remodeling.

This paper shows a CTRB2 deletion variant increases pancreatic cancer risk by causing ER stress and inflammation in mice, using a new genetic model.