Alexandre Murza

The paper evaluates the antibacterial activity of tomatidine analogs against various bacterial strains, identifying TM-184 as effective against Gram-positive, Gram-negative, and multidrug-resistant bacteria, with in vivo efficacy in a mouse model.

This study identifies AngII analogs with modified C-terminal peptides that selectively engage Gq or β-arrestin pathways, showing differential effects on cardiac function and blood pressure in rats.