Author

Justin Martel

Université de Sherbrooke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mixed model· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Brian J. HolleraniD· 2 shared Hugo GiguèreiD· 2 shared Mannix Auger‐MessieriD· 2 shared Richard LeduciD· 2 shared Alexandre MurzaiD· 1 shared Andréanne Laniel· 1 shared Antoine DésiletsiD· 1 shared Christine L. LavoieiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersPharmacology & Toxicology

Brian J. HolleranORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Isoform-Dependent Loss- and Gain-of-Function of the Gαs K53N Variant in Human Disease

Haoran Geng, Justin Martel, Brian J. Holleran, Andréanne Laniel, Erwan Lanchec, Antoine Désilets, Hugo Giguère, Jean‐Luc Parent, Richard Leduc, Louis-Philippe Picard, Mannix Auger‐Messier, Christine L. Lavoie

This study investigates the K53N mutation in Gs isoforms, revealing isoform-specific loss- and gain-of-function effects contributing to disease mechanisms in endocrine and cardiac tissues.

bioRxiv · Sep 2, 2025 · PreprintPharmacology & Toxicology

Tunable Bias Signaling of the Angiotensin II Type 1 Receptor for Inotropy via C-Terminal Peptide Modifications and Allosteric Site Targeting

Margot Hadjadj, Justin Martel, Marie-Frédérique Roy, Malihe Hassanzadeh, Hugo Giguère, Alexandre Murza, Brian J. Holleran, Yoon Namkung, Ulrike Froehlich, Richard Leduc, Mannix Auger‐Messier, Stéphane A. Laporte, Pierre‐Luc Boudreault

This study identifies AngII analogs with modified C-terminal peptides that selectively engage Gq or β-arrestin pathways, showing differential effects on cardiac function and blood pressure in rats.

bioRxiv · Aug 13, 2025 · PreprintMolecular Biology