Author

Brian M. Polster

University of Maryland, BaltimoreORCID 0000-0003-2571-7510Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Boris Piskoun· 2 shared Courtney RobertsoniD· 2 shared Naibo ZhangiD· 2 shared Apurva BorcariD· 1 shared Ayodele Jaiyesimi· 1 shared Brian A. RoelofsiD· 1 shared Chinmoy SarkariD· 1 shared Evan A. BordtiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

Boris Piskoun

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 14, 2026

HAPI Cells are SIM-A9-related Mouse Microglial Cells Useful for In Vitro Modeling of Microglial Immunometabolism

Ryan P. Mayers, Sausan M. Jaber, Nicolas A. Verhoeven…·Brian M. Polster

The paper identifies HAPI cells as mouse microglial cells related to SIM-A9 and validates their use for in vitro immunometabolism studies.

1 citation

mousestatistical model

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Cell BiologyFree Radical Biology and MedicinePeer-reviewedSep 9, 2025

CRABS-ROC, A Respirometry Protocol For Overcoming Substrate Limitations, Reveals Excess Brain Mitochondrial Complex I Capacity

Naibo Zhang, Brian A. Roelofs, Evan A. Bordt…·Brian M. Polster

CRABS-ROC, a respirometry protocol, overcomes substrate limitations to reveal excess mitochondrial Complex I capacity in neurons and detect hidden Complex I deficits in mutant mitochondria.

DOI 10.1016/j.freeradbiomed.2025.09.011

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NeurosciencebioRxivPreprintMay 6, 2025

Idebenone Enhances the Early Microglial Response to Traumatic Brain Injury and Mitigates Acute Gene Expression Changes to Ephrin-A and Dopamine Signaling Pathways

Hyehyun Hwang, Chinmoy Sarkar, Boris Piskoun…·Brian M. Polster

This study shows idebenone enhances microglial activation after TBI but reduces gene expression changes in dopamine and Ephrin-A signaling pathways.

DOI 10.1101/2025.05.06.652467

mousebulk RNA-seq

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