Mislav Acman

This paper introduces BOB-seq, a method for isoform-resolved multiplexed RNA sequencing that uses bioorthogonal barcoding to capture full-length transcripts and improve splicing effect detection.

This study identifies microbial hallmarks of sepsis using metagenomic data and shows that polymicrobial communities, not single pathogens, are key in sepsis diagnosis.

The paper estimates changes in SARS-CoV-2 transmissibility using a phylogeny-based metric, finding that Delta is the most transmissible clade and transmissibility within clades slightly decreases over time.

This study tests if recurrent mutations in SARS-CoV-2 are linked to increased transmissibility and finds no significant association.

The paper identifies pre-existing bedaquiline resistance variants in Mycobacterium tuberculosis genomes before clinical use of the drug, highlighting the need for rapid susceptibility testing.

This study uses network analysis of over 10,000 bacterial plasmids to uncover population structure, gene content correlations, and drivers of horizontal gene transfer.