MicrobiologybioRxivPreprint
In HSV-1, the LAT Enhancer Drives Pre-IE VP16 Transcription to Initiate Reactivation
Ziyun A. Ye, Mason A. Shipley, Pankaj Singh, Donna M. Neumann
This paper shows that the LAT enhancer drives VP16 transcription during HSV-1 reactivation, overcoming CTCF and cohesin-mediated silencing during latency.
DOI 10.64898/2026.01.06.697999