Junyi Tao

This study shows that short-term oxycodone exposure in mice causes delayed and persistent gut microbiome changes that persist for at least 70 days post-treatment.

The paper shows that neonatal morphine exposure in HIV-infected mice causes long-term neuroimmune and anxiety-related transcriptional changes in specific brain cell types.

The paper uses single-cell RNA sequencing to show that neonatal morphine exposure disrupts midbrain gene expression in adolescent mice, but probiotic treatment reverses these effects.

This study shows that gut microbial dysbiosis drives anxiety-like behavior during morphine withdrawal and that probiotics can reduce this behavior.