Sabita Roy

This study shows that short-term oxycodone exposure in mice causes delayed and persistent gut microbiome changes that persist for at least 70 days post-treatment.

This paper shows that KSHV-infected cells can form tumors in immunocompetent mice when pretreated with EcoHIV and morphine, mimicking human KS lesions.

This paper shows that KSHV uses eIF5B to mimic hypoxia and support viral replication and oncogenesis by altering translation initiation.

The paper uses single-cell RNA sequencing to show that neonatal morphine exposure disrupts midbrain gene expression in adolescent mice, but probiotic treatment reverses these effects.

This study shows that cross-fostering opioid-exposed pups to naive dams rescues gut dysbiosis and chromatin-related transcriptional changes, suggesting microbiome-driven mechanisms in opioid-induced developmental injury.

This study shows that B12 supplementation promotes gut dysbiosis and inflammation, which enhances myelopoiesis in Tet2-deficient mice, suggesting a microbiome-mediated mechanism for clonal hematopoiesis.

This study shows that gut microbial dysbiosis drives anxiety-like behavior during morphine withdrawal and that probiotics can reduce this behavior.