Author

Kalyani R. Patel

Cincinnati Children's Hospital Medical CenterORCID 0000-0003-2654-5386Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adam B. Castoreno· 1 shared Alexandria M. DoerfleriD· 1 shared Andras Attila HeczeyiD· 1 shared Angshumoy RoyiD· 1 shared Ayrea E. HurleyiD· 1 shared Barry Zorman· 1 shared Christine BeetoniD· 1 shared Christopher J. WalkeyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Adam B. Castoreno

Mutual co-authors in cluster

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2 papers

Recent·Most cited

GenomicsJournal of HepatologyPeer-reviewedFeb 28, 2026

Asynchronous Transitions from Hepatoblastoma to Carcinoma in High-Risk Pediatric Tumors

Xinjian Yu, Stephen Frederick Sarabia, Martin Urbicain…·Pavel Sumazin

The paper characterizes hepatoblastoma with carcinoma features (HBCs) using multi-omics data, revealing their heterogeneous composition, worse outcomes, and origin from arrested HB cells due to WNT signaling.

1 citation

humansnRNA-seq

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GeneticsScience Translational MedicinePeer-reviewedFeb 12, 2025

In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene

Marco De Giorgi, So Hyun Park, Adam B. Castoreno…·William R. Lagor

This paper introduces a method to increase the proportion of correctly repaired hepatocytes in the liver through transient gene inhibition and transgene delivery, achieving a 25% increase in targeted cells and five-fold transgene expression.

8 citations

mouseCRISPR screen

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