Author

Christopher J. Walkey

Baylor College of MedicineORCID 0000-0002-1471-0447Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

M. Cecilia LjungbergiD· 2 shared Marcel A. ChuecosiD· 2 shared Marco De GiorgiiD· 2 shared William R. LagoriD· 2 shared Aaron R. CoxiD· 1 shared Adam B. Castoreno· 1 shared Alexa E. MartineziD· 1 shared Alexandria M. DoerfleriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

M. Cecilia LjungbergORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene

Marco De Giorgi, So Hyun Park, Adam B. Castoreno, Mingming Cao, Ayrea E. Hurley, Lavanya Saxena, Marcel A. Chuecos, Christopher J. Walkey, Alexandria M. Doerfler, Mia N. Furgurson, M. Cecilia Ljungberg, Kalyani R. Patel, Sarah Hyde, Tyler Chickering, Stephanie Lefebvre, , William R. Lagor

This paper introduces a method to increase the proportion of correctly repaired hepatocytes in the liver through transient gene inhibition and transgene delivery, achieving a 25% increase in targeted cells and five-fold transgene expression.

Science Translational Medicine · Feb 12, 2025Peer-reviewedGenetics

A Comprehensive Atlas of AAV Tropism in the Mouse

Christopher J. Walkey, Kathy J. Snow, Jote Bulcha, Aaron R. Cox, Alexa E. Martinez, M. Cecilia Ljungberg, Denise Grant Lanza, Marco De Giorgi, Marcel A. Chuecos, Michele Alves‐Bezerra, Carlos Perfecto Flores Suarez, Sean Michael Hartig, Susan Galloway Hilsenbeck, Chih‐Wei Hsu, Ethan Saville, , William R. Lagor

This paper maps the tissue tropism of ten AAV serotypes in mice after systemic delivery, identifying liver preference and unexpected transduction in adrenals, testes, and ovaries.

Molecular Therapy · Jan 25, 2025Peer-reviewedMolecular Biology