Niklas Mähler

This paper provides consensus recommendations for standardizing bioinformatics practices in clinical whole genome sequencing to ensure accuracy, reproducibility, and comparability of results.

The paper presents an improved chromosome-scale genome assembly for Populus tremula and integrates population genetics and genomics data to study leaf physiognomy traits through GWAS and functional analysis.

The paper investigates the genetic architecture of gene expression variation in Populus tremula, finding that eQTLs are more common in regulatory regions and that network connectivity correlates with selective constraint.