Ariel Chernomoretz

The paper uses network analysis of protein binding sites to reveal organizational patterns across scales, showing both diversification within protein categories and local similarities across boundaries.

The paper identifies a reversible apoptotic checkpoint in aging mouse hippocampal neuroblasts that limits neurogenesis and can be mitigated by voluntary running.

The paper examines how neuronal development and different stimulation modalities affect activity-dependent gene expression in neurons.

This study uses snRNA-seq to track the transcriptional changes in adult hippocampal neurons from birth to maturity, identifying key transcription factors and molecular switches involved in their differentiation.

The paper analyzes 5' splicing site sequences across fungi, metazoa, and plants to identify conserved and divergent signals, revealing lineage-specific two-site coupling patterns that reflect splicing regulation differences.

GENis is an open-source forensic DNA database system that supports local, regional, and national levels with security features and a Bayesian framework for cold hit analysis.

ASpli2 identifies changes in both annotated and novel alternative splicing events using simulated and real RNA-Seq data, improving recall while maintaining precision.

The paper presents a large-scale cancer pharmacogenomic screen with 11,576 experiments on 910 drug combinations across 85 cancer cell lines, enabling crowd-sourced prediction of synergistic drug pairs and biomarkers.