Alejandro Fabián Schinder

The paper identifies a reversible apoptotic checkpoint in aging mouse hippocampal neuroblasts that limits neurogenesis and can be mitigated by voluntary running.

This study shows that audiovisual gamma stimulation improves hippocampal neurogenesis and circuit plasticity in aging mice by enhancing progenitor cell activity and synaptic integration.

This study shows that the dentate gyrus supports cognitive flexibility in spatial navigation by enabling efficient adaptation to changing environments.

This study uses snRNA-seq to track the transcriptional changes in adult hippocampal neurons from birth to maturity, identifying key transcription factors and molecular switches involved in their differentiation.

The paper shows that young adult-born neurons can reconfigure CA3 spatial maps, while mature neurons cannot, suggesting a unique role in pattern separation.

This study investigates the connectivity dynamics between adult-born granule cells and inhibitory interneurons in the hippocampus, revealing distinct developmental patterns and functional roles.