Daniela J. Di Bella

The paper identifies a reversible apoptotic checkpoint in aging mouse hippocampal neuroblasts that limits neurogenesis and can be mitigated by voluntary running.

The paper induces menstruation in mice to study endometrial shedding regulation, revealing a new paradigm for spatially regulated fibroblast differentiation.

The paper shows pyramidal neurons influence the survival and identity of specific interneuron subtypes through non-synaptic mechanisms.

This study uses snRNA-seq to track the transcriptional changes in adult hippocampal neurons from birth to maturity, identifying key transcription factors and molecular switches involved in their differentiation.

The paper introduces a multi-donor brain organoid model called Chimeroids to study individual genetic variation in neurotoxin susceptibility.

The paper generates a single-cell RNA-seq and ATAC-seq atlas of the developing mouse neocortex and reconstructs developmental trajectories to infer gene regulatory programs and identify lineage-specific developmental abnormalities.

The paper develops genetic tools to dissect glutamatergic neuron subpopulations and their developmental trajectories in the cerebral cortex.