Author

G.J. Lockbaum

University of Massachusetts Chan Medical SchoolORCID 0000-0003-2720-6984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Akbar AliiD· 1 shared Celia A. SchifferiD· 1 shared E.A. NalivaikaiD· 1 shared Florian LeidneriD· 1 shared Gily S. NachumiD· 1 shared K. KosovrastiiD· 1 shared Linah N. RusereiD· 1 shared M. HenesiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Akbar AliORCID

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1 paper

Recent·Most cited

Molecular BiologyACS Infectious DiseasesPeer-reviewedDec 13, 2018

Structural Adaptation of Darunavir Analogs Against Primary Resistance Mutations in HIV-1 Protease

G.J. Lockbaum, Florian Leidner, Linah N. Rusere…·Celia A. Schiffer

The paper investigates how structural changes in HIV-1 protease affect the potency of Darunavir and its analogs against primary resistance mutations using crystal structures and vdW interaction analysis.

37 citations

humanproteomics

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