Hristo Todorov

The paper analyzes miRNA expression and co-targeting relationships during mouse cerebral cortex development, identifying stage-specific hubs and enhanced transcriptional silencing effects of miRNA pairs.

This study identifies miR-92a-3p as a regulator of RBFOX2 expression, which controls the splicing transition from neural progenitors to neurons in the developing mouse cortex.

Cortexa provides a web-portal with standardized RNA-sequencing data and tools for analyzing gene expression and alternative splicing in the mouse brain.

The paper identifies sustained freezing during prolonged threat memory retrieval as an anxiety-endophenotype biomarker in both male and female inbred mice, with sex-specific transcriptomic differences in brain regions associated with psychiatric disorders.

The paper shows that reactivation of inactive X-chromosome alleles in female neural cells during differentiation enhances resilience to X-linked neurodevelopmental disorders.