Beat Lutz

This study shows that deleting glucocorticoid receptors in postnatal oligodendrocyte precursor cells reduces oligodendrocyte density, alters hippocampal activity, and impairs memory in adult mice.

This study shows that deleting Shank3 in glutamatergic neurons of the anterior insular cortex causes autism-like behaviors and circuit dysfunction in mice.

This study introduces NanoRibolyzer, a long-read nanopore sequencing method to map pre-rRNA processing and modification at single-nucleotide resolution, revealing cleavage sites and modification patterns.

This study shows that restoring CB1R in the anterior insular cortex of CB1R-deficient mice normalizes social novelty discrimination and reduces anxiety-like behavior without affecting other behaviors.

ClearFinder provides a Python GUI for cell annotation in cleared mouse brains, improving accessibility and enabling statistical analysis and visualization.

The paper identifies sustained freezing during prolonged threat memory retrieval as an anxiety-endophenotype biomarker in both male and female inbred mice, with sex-specific transcriptomic differences in brain regions associated with psychiatric disorders.

This study shows that adolescent THC exposure causes microglial apoptosis in the mPFC, which is worsened by 16p11.2 duplication, leading to social memory deficits via microglial Cnr1.

This study identifies Dusp6 as a key inhibitor of oligodendrocyte plasticity after spinal cord injury and shows that its inactivation promotes axonal regrowth by converting oligodendrocytes into repair cells.

The paper shows that peripheral CB1R blockade enhances non-emotional memory through an adrenergic-dependent mechanism in mice.