David C. Stieg

This study shows cyclin C maintains autophagy-lysosome pathway function in pancreatic development and suppresses cancer by eliminating damaged cells, with potential therapeutic implications for pancreatic neoplasms.

This study shows cyclin C's mitochondrial role in promoting oxidative stress-induced cell death in yeast, independent of its transcriptional function.

This study shows cyclin C promoter occupancy changes under stress, directing transcriptional reprogramming through CKM movement and activity.