Author

Simmone D’souza

University of LethbridgeORCID 0000-0003-2750-8675Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Annie Y. CheniD· 1 shared Carla S. CoffiniD· 1 shared Guido van MarleiD· 1 shared Jennifer A. CorcoraniD· 1 shared Maulik D. BadmaliaiD· 1 shared Milan S. Heck· 1 shared Scott TersteegiD· 1 shared Trushar R. PateliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

Annie Y. ChenORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintMay 14, 2025

A Guanine-quadruplex located on the negative strand of the hepatitis C virus facilitates efficient genomic RNA synthesis

Simmone D’souza, Scott Tersteeg, Maulik D. Badmalia…·Trushar R. Patel

This paper identifies a conserved G4 structure in the HCV negative strand 3 UTR that is essential for efficient RNA synthesis by facilitating NS3 helicase recruitment and NS5B polymerase access.

DOI 10.1101/2025.05.14.654041

humanexperimental assay

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