Lu Fan

PhageHost-GNN: novelty-aware and locally adaptable strain-level Klebsiella-phage prediction

PhageHost-GNN predicts strain-level Klebsiella-phage interactions using a novelty-aware framework, achieving high AUPRC scores in in silico evaluations and showing advantages in handling novel data.

Bacterial DNA methylation amplifies the shared A-to-G and G-to-A substitution bias in nanopore sequencing

The paper identifies a shared A-to-G and G-to-A substitution bias in nanopore sequencing, amplified by bacterial DNA methylation, and shows this bias is concentrated around methylation motifs.

A regulator controls both DNA damage response and anti-phage defense networks in Moraxellaceae

This study identifies a WYL family protein in Moraxellaceae that regulates both DNA damage response and anti-phage defense networks, enhancing understanding of bacterial immunity and antibiotic resistance.

Recovery of high-qualitied Genomes from a deep-inland Salt Lake Using BASALT

This study introduces BASALT, a metagenomic binning toolkit that improves MAG recovery and quality, and applies it to a Salt Lake sediment sample to discover new Lokiarchaeotal MAGs.