David M. Parichy

This study identifies a zebrafish mutation in ddx49 causing differential cell-type vulnerability in pigment cells due to impaired ribosome biogenesis.

The paper investigates the developmental and evolutionary origins of white pigment cells in cyprinid fishes, revealing convergent mechanisms across species.

The paper shows how graded BMP signals influence pigment cell development and color in fish, affecting adult patterns and behavior through conserved mechanisms.

This study investigates the genomic and genetic factors underlying speciation and pigment pattern diversification in Danio fishes, revealing introgression, functional divergence of specific genes, and evolutionary changes in protein and regulatory sequences.

The paper identifies a gene involved in pigment cell communication that governs color pattern formation in zebrafish and anemonefish.

The paper identifies BMP and Agouti signaling pathways that drive the transdifferentiation of melanophores to leucophores in zebrafish fins.

The paper uses single-cell transcriptomics to study zebrafish skin development, identifying new cell types and signaling mechanisms involved in pigment pattern and scale formation.

The paper compares zebrafish Switch reporter transgenes to identify those with optimal recombination efficiency and expression patterns for lineage labeling.

The paper introduces quantitative metrics based on information theory to analyze pigment patterns in Danio fishes, showing they can distinguish pattern types and detect mutation effects.

This study identifies the developmental origin and genetic mechanisms of red coloration in D. albolineatus, showing parallels with bird coloration mechanisms.

This study shows thyroid hormone regulates dermal development and scale formation in zebrafish through nuclear hormone receptors, coupling skin growth with body size.

This study identifies Jam3b as essential for melanophore survival and stripe patterning in zebrafish by analyzing a mutant with defects in pigment cell arrangement and adhesion.

This study identifies a complex genetic architecture underlying stripe and spot patterns in zebrafish relatives D. quagga and D. kyathit, revealing multiple loci and epistatic interactions.

The paper shows zebrafish stripe patterns arise from in situ differentiation of iridophore crystallotypes, not migration, with distinct transcriptomic and physiological states in stripe and interstripe regions.

The paper investigates how thyroid hormone regulates different maturation paths in zebrafish pigment cell lineages through transcriptomic profiling and trajectory analysis.

The paper identifies two distinct leucophore populations in zebrafish, showing their different origins and functional roles through single-cell transcriptomics and other analyses.

The paper identifies Endothelin-3 as a factor contributing to differences in iridophore development and pigment patterns between Danio rerio and D. nigrofasciatus.

The paper investigates the role of Wnt/β-catenin signaling in zebrafish scale development and identifies its integration with Eda and Fgf signaling to coordinate morphogenesis.

This study uses microCT to analyze zebrafish skeletons, identifying phenotypes linked to human diseases and showing how deep phenotyping improves mutant discrimination.