Susann Boretius

This study transplants human iPSC-derived cardiomyocyte aggregates into non-human primates with myocardial infarction, showing efficient engraftment and functional recovery with lower cell doses than previous single-cell approaches.

This study examines natural cardiovascular aging in non-human primates, finding histological and molecular changes associated with aging, including fibrosis, inflammation, and atherosclerosis.

The paper shows that deleting EPO in the forebrain of mice leads to increased expression of EPOR and EphB4, which may explain the lack of cognitive deficits in these mutants.

This study investigates how erythropoietin (EPO) and its receptor (EPOR) regulate oligodendrocyte lineage dynamics in the adult mouse hippocampus, showing EPO promotes differentiation and maturation, and suggests potential therapeutic applications for remyelination.

This study shows that erythropoietin treatment improves behavioral and phenotypical symptoms in Zbtb20+/- mice, a model of Primrose syndrome.

The paper assesses consistency of rat fMRI results across 12 centers using a unified pipeline and identifies variability due to experimental differences.

The paper compares the effects of two anesthetic protocols on marmoset brain networks, finding that medetomidine with isoflurane preserves functional network structure better than isoflurane alone.

This paper introduces TQ-SILiCON, a method that fuses quantitative susceptibility maps with T1-weighted images to improve brain tissue contrast in primates, enhancing segmentation of subcortical and white matter structures.

This study identifies species-specific fMRI signatures of anesthesia-induced burst-suppression in primates and rodents, showing differences in brain regions involved.

This study shows that CMTM5 deficiency in oligodendrocytes leads to progressive axonopathy, suggesting its role in maintaining axonal integrity rather than myelin formation.

The paper shows that VIP neurons in reeler mice, lacking cortical layers, have increased callosal connectivity and altered long-range inputs, suggesting functional circuits can form without layer organization.

This study evaluates how medetomidine administration protocols affect the temporal stability of fMRI readouts in anesthetized rats over six hours.