NeuroscienceAlzheimer s & DementiaPeer-reviewed
A novel small molecule screening platform for disrupting toxic tau oligomers in cells
Chih Hung Lo, Colin Kin‐Wye Lim, Zhipeng Ding…·Jonathan N. Sachs
The paper develops a FRET-based biosensor platform to screen small molecules targeting toxic tau oligomers, identifying MK-886 as a compound that disrupts tau oligomers and reduces cytotoxicity.
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