Author

David C. Hess

University of Nevada, RenoORCID 0000-0003-2821-1021Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Mark PandoriiD· 2 shared Andrew J. GorzalskiiD· 1 shared Chi N. Hua· 1 shared Christina A. CuomoiD· 1 shared Craig M. StephensiD· 1 shared Danielle Denise Siao· 1 shared Eileen Wagner· 1 shared Emily Schneider· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Mark PandoriORCID

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2 papers

Recent·Most cited

GeneticsAntimicrobial Agents and ChemotherapyPeer-reviewedSep 22, 2025

Acquired Amphotericin B Resistance Attributed to a Mutated ERG3 in Candidozyma auris

Lauryn Massic, Laura A. Doorley, Sarah J Jones…·Mark Pandori

This paper describes a clinical case of acquired amphotericin B resistance in Candidozyma auris due to a frameshift mutation in ERG3, showing a fitness cost associated with altered sterol production.

14 citationstop 1%

whole-genome sequencingexperimental assay

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BioinformaticsPLoS ONEPeer-reviewedFeb 16, 2023

GAMBIT (Genomic Approximation Method for Bacterial Identification and Tracking): A methodology to rapidly leverage whole genome sequencing of bacterial isolates for clinical identification

Jared Lumpe, Lynette Gumbleton, Andrew J. Gorzalski…·Mark Pandori

GAMBIT uses k-mer based strategies and a curated database to identify bacteria from whole genome sequencing with confidence thresholds to reduce false identifications.

32 citationstop 2%

bacteria (other)whole-genome sequencing

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