Laura A. Doorley

This study identifies loss-of-function mutations in RBA1 as a convergent adaptation in C. auris that enhances its ability to adhere, form biofilms, and cause infections.

This paper describes a clinical case of acquired amphotericin B resistance in Candidozyma auris due to a frameshift mutation in ERG3, showing a fitness cost associated with altered sterol production.

The paper develops an EPIC gene-editing system for Candida auris to study the impact of FKS1 S639F mutation on echinocandin resistance, showing increased resistance and altered cell wall composition.

The paper identifies copy number variations in fluconazole resistance genes in Candida parapsilosis isolates using whole-genome sequencing and GWAS.