Lorenz Adlung

This study shows intestinal stem cells use TLR2 to sense microbes, coordinating epithelial defense and regeneration.

The paper identifies norepinephrine as a trigger of macrophage efferocytosis in brown adipose tissue, linking sympathetic signaling to metabolic adaptation through β2-adrenergic and Axl/Mertk pathways.

This study uses snRNA-seq to analyze cold-induced changes in brown adipocyte subtypes in mice, identifying ChREBP's role in lipogenic adipocyte identity and plasticity.

This study uses longitudinal scRNA-seq data from a mouse colitis model to build ODE-based models of immune dynamics, validating predictions with flow cytometry and human IBD gene expression data.

The paper models single-cell variability in JAK2/STAT5 signaling and cytoplasmic volume to explain how erythroid progenitor cells transition from binary survival/apoptosis decisions to graded population responses upon Epo stimulation.