Mohammed Rabiul Hosen

This study identifies ceramide-driven lipotoxicity as a driver of calcific aortic valve disease and shows that SPT inhibition can reverse disease progression in vivo.

This study shows that anemia in coronary artery disease patients increases release of red blood cell-derived extracellular vesicles (REVs) that promote endothelial dysfunction by enhancing nitric oxide consumption and oxidative stress.

This study compares the effects of acute and chronic blood loss anemia on vascular function after myocardial infarction in mice, finding both types impair endothelial function with chronic anemia additionally reducing vascular smooth muscle contractility.