Patricia Wischmann

Large extracellular vesicles derived from red blood cells in coronary artery disease patients with anemia promote endothelial dysfunction

This study shows that anemia in coronary artery disease patients increases release of red blood cell-derived extracellular vesicles (REVs) that promote endothelial dysfunction by enhancing nitric oxide consumption and oxidative stress.

Distinct effects of acute and chronic blood loss anemia on vascular function after acute myocardial infarction

This study compares the effects of acute and chronic blood loss anemia on vascular function after myocardial infarction in mice, finding both types impair endothelial function with chronic anemia additionally reducing vascular smooth muscle contractility.