Junhui Peng

The paper compares immune responses across five Drosophilidae species to bacterial infection, finding that clearance, not tolerance, drives differences in survival rates and identifying new antimicrobial peptides.

The paper identifies MOSN, a novel sex-specifically spliced neuronal gene in Aedes aegypti, conserved in other mosquito species but absent in Drosophila, with distinct protein isoforms and a duplicated domain.

The paper predicts protein-protein interactions in Drosophila using AlphaFold2-multimer, highlighting the role of intrinsically disordered regions and providing an interactive interface for exploration.

The paper identifies key transcription factors regulating de novo genes using single-cell RNA sequencing and genetic tools in Drosophila.

This study identifies CDCA7 as a hemimethylated DNA sensor that interacts with HELLS to facilitate nucleosome remodeling and DNA methylation maintenance.