Li Zhao

The paper compares immune responses across five Drosophilidae species to bacterial infection, finding that clearance, not tolerance, drives differences in survival rates and identifying new antimicrobial peptides.

The paper identifies MOSN, a novel sex-specifically spliced neuronal gene in Aedes aegypti, conserved in other mosquito species but absent in Drosophila, with distinct protein isoforms and a duplicated domain.

This paper investigates HP6/Umbrea's role as a plasticizer of HP1a condensates, showing it enhances permeability to transcriptional machinery without altering phase separation properties.

The paper investigates how genetic changes in CO2-sensing neurons drive divergent oviposition preferences in Drosophila species.

The paper predicts protein-protein interactions in Drosophila using AlphaFold2-multimer, highlighting the role of intrinsically disordered regions and providing an interactive interface for exploration.

The paper identifies key transcription factors regulating de novo genes using single-cell RNA sequencing and genetic tools in Drosophila.

The paper develops Bayesian methods to quantify transcriptome turnover across species, finding accelerated gene expression changes in testes and accessory glands of Drosophila species.

The paper identifies a core gene set for cross-species cell type classification in Drosophila and shows genome organization influences transcriptional bursting and de novo gene origination during spermatogenesis.

The paper identifies a lipid desiccation barrier in Drosophila pupae and adults, showing its role in preventing dehydration during metamorphosis and its adaptation in different species.

This study identifies CDCA7 as a hemimethylated DNA sensor that interacts with HELLS to facilitate nucleosome remodeling and DNA methylation maintenance.

This study overexpresses PpGL2 in soybean to improve drought tolerance, showing reduced oxidative stress and enhanced growth under drought conditions.

This study identifies two rapidly evolving genes in Aedes aegypti mosquitoes that enable extended egg retention during drought, enhancing reproductive resilience.

The paper uses scRNA-seq to analyze X-chromosome transcription in Drosophila testis, finding that dosage compensation occurs in somatic and pre-meiotic cells but not in meiotic or post-meiotic cells.

The paper presents an improved Aedes aegypti genome assembly, AaegL5, which enhances biological understanding and vector control efforts by resolving key genomic features and identifying new targets for intervention.