Author
Queen's University BelfastORCID 0000-0003-2866-942XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Alice T. Browne, Chris McCann, William J. McDaid…·Emma M. Kerr
This study shows that mutant KRAS dosage affects therapeutic response in lung cancer, with higher dosages linked to resistance to platinum therapy and sensitivity to pS6K inhibition.
Aidan O’Brien, Hyunkyung Kong, Harsh Patel…·Laufey Thora Amundadottir
The paper identifies functional variants and VNTRs at the 5p15.33 locus using fine-mapping, MPRA, and CRISPRi screens, revealing their role in cancer susceptibility through antagonistic pleiotropy.
Kate Mackie, Harriet Kemp, Andrea Gunnell…·Syed Haider
The paper identifies CCDC88C as a risk gene for ER-positive breast cancer by analyzing functional variants from GWAS signals using a massively parallel reporter assay.