Simón Álamos

The paper maps transcription factor effector domains in plants and compares their function across eukaryotes, revealing conserved and lineage-specific regulatory principles.

The paper models variability in Nicotiana benthamiana transient expression and provides guidelines for minimizing it through experimental design and power analysis.

The paper develops a toolkit of chromatin regulators with cross-kingdom functionality for programmable transcriptional repression and activation in eukaryotic cells.

This study introduces ENTRAP-seq, a method to measure transcriptional regulator activity in plants, and identifies novel regulatory domains in viral proteins.

This study engineers cytokinin regulators in Arabidopsis to modulate root development by tuning gene expression through synthetic biology.

The paper shows that DRMY1 sustains translation of cytokinin signaling inhibitors, ensuring robust sepal development in Arabidopsis by maintaining auxin patterning.

The paper uses a minimal synthetic enhancer in Drosophila to show that a single Dorsal binding site can regulate transcriptional engagement probability and timing in response to a morphogen gradient.

The paper introduces Loop assembly, a method for efficiently and parallelly constructing large DNA circuits using two Type IIS restriction endonucleases and standardised parts.