Developmental BiologybioRxivPreprint
Coordinated repression of totipotency-associated gene loci by histone methyltransferase EHMT2 through binding to LINE-1 regulatory elements
Kaushiki Chatterjee, Christopher M. Uyehara, Kritika Kasliwal…·Matthias Stadtfeld
The paper identifies EHMT2's role in repressing totipotency-associated gene loci in mESCs by binding to LINE-1 elements and modulating gene expression during the mESC-to-2CLC transition.