Author

Nicholas M. Anthony

Northwestern UniversityORCID 0000-0003-2882-2471Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:imaging· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:Hi-C· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Igal G. SzleiferiD· 3 shared Jane FrederickiD· 3 shared Luay Matthew AlmassalhaiD· 3 shared Vadim BackmaniD· 3 shared Cody L. DuntoniD· 2 shared David VanDerwayiD· 2 shared Emily M. Pujadas-LiwagiD· 2 shared I Chae YeiD· 2 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiophysics

Igal G. SzleiferORCID

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3 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedJul 22, 2025

Leveraging chromatin packing domains to target chemoevasion in vivo

Jane Frederick, Ranya K. A. Virk, I Chae Ye…·Vadim Backman

This study develops a physics-based model linking chromatin organization to chemoevasion, identifies TPR compounds that enhance chemotherapy efficacy in ovarian cancer.

7 citations

humanChIP-seq

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BiophysicsPLoS ONEPeer-reviewedMay 28, 2024

Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure

Anne R. Shim, Jane Frederick, Emily M. Pujadas-Liwag…·Vadim Backman

This study shows that formamide in 3D FISH distorts nanoscale chromatin structure, while alternative methods like RASER-FISH and CRISPR-Sirius have minimal impact.

14 citations

imagingexperimental assay

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GenomicsMicroscopy and MicroanalysisPeer-reviewedJul 30, 2020

Nanoscale Chromatin Imaging and Analysis (nano-ChIA) platform bridges 4-D chromatin organization with molecular function

Yue Li, Adam Eshein, Ranya K. A. Virk…·Vadim Backman

The paper introduces a nano-ChIA platform that combines electron tomography and superresolution imaging to study chromatin structure and dynamics at the single-nucleosome level in live cells.

8 citations

humanHi-C

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