Irene Otero‐Muras

This paper introduces PROMETEO, a genetic-circuit framework that programs microbial population composition through asymmetric circuits, enabling functional organization and efficient biotransformation.

The paper introduces BiosInt, a genetic circuit for dynamic pathway regulation in biomanufacturing, validated through synthetic datasets and applied to flavonoid production.

This paper presents an optimization-based method to design synthetic gene circuits with specified bifurcation diagrams, focusing on mushroom bifurcation for applications in biosensors and synthetic biology.

OptDesign identifies optimal strain design strategies for biochemical production in E. coli by combining regulation and knockout interventions using a two-step approach.

The paper develops a generalized method to detect switch-like bistability in chemical reaction networks with conservation laws, validated on known bistable motifs.