Pablo Carbonell

BiosInt: Biosensor-based smart design of pathway dynamic regulation for industrial biomanufacturing

The paper introduces BiosInt, a genetic circuit for dynamic pathway regulation in biomanufacturing, validated through synthetic datasets and applied to flavonoid production.

Sensbio: An online server for biosensor design

Sensbio identifies potential TF-ligand pairs by comparing input molecules to a TF-ligand database and using a predictive model.

Galaxy-SynBioCAD: Automated Pipeline for Synthetic Biology Design and Engineering

Galaxy-SynBioCAD provides an automated pipeline for synthetic biology design and engineering, achieving an 83% success rate in retrieving validated pathways.

Developing an enzyme selection tool supporting multiple hosts contexts

The paper updates Selenzyme, an enzyme selection tool, to support multiple host contexts for better affinity comparison and optimal host selection.

PartsGenie: an integrated tool for optimising and sharing synthetic biology parts

PartsGenie is a tool for designing and sharing synthetic biology parts, integrating optimization, data standards, and repository access.

Selenzyme: Enzyme selection tool for pathway design

Selenzyme is an online tool that helps select enzymes for metabolic pathway design by analyzing sequence, reaction, and organism-related data.

RetroPath2.0: A retrosynthesis workflow for metabolic engineers

RetroPath2.0 is an open-source retrosynthesis workflow that streamlines pathway design for metabolic engineering by using generalized reaction rules and KNIME.

Molecular structures enumeration and virtual screening in the chemical space with RetroPath2.0

The paper demonstrates the use of RetroPath2.0 for molecular structure enumeration and virtual screening in chemical space, including applications for glass transition temperature prediction and antibacterial activity optimization.