Marcus Kaiser

Rewiring the Human Brain: On the Fabric of Associative Thinking

This paper proposes a model for how structural plasticity enables the formation of concept engrams in the human brain through synaptic creation, and demonstrates how activating a concept can trigger related concepts via percept-concept loops.

Transcutaneous auricular Vagus nerve stimulation for working memory enhancement: A comparative study of electrical and ultrasound stimulation

This study compares the effects of electrical and ultrasound transcutaneous auricular vagus nerve stimulation on working memory in healthy adults, finding that electrical stimulation significantly improves performance while ultrasound shows a similar trend but less statistical significance.

Selective enhancement of fronto-temporal mechanisms for adaptive memory

This study uses transcranial ultrasound stimulation to enhance memory performance in macaques by targeting specific fronto-temporal brain regions.

Transcutaneous auricular vagus nerve stimulation enhances emotional bias towards happiness in healthy young adults: A comparative study of electrical and ultrasound stimulation

This study compares the effects of electrical and ultrasound transcutaneous auricular vagus nerve stimulation on emotional bias in healthy adults, finding both methods enhance positive emotional interpretation.

Comparing Electrical and Ultrasound Transcutaneous Vagus Nerve Stimulation (taVNS) on Associative Memory

This study compares electrical and ultrasound transcutaneous vagus nerve stimulation on associative memory, finding no improvement in recall accuracy but faster response times with electrical stimulation.

Ultrasound transcutaneous auricular vagus nerve stimulation enhances semantic processing

Ultrasound-based taVNS improves semantic retrieval efficiency in healthy adults compared to sham and baseline.

Understanding the high-order network plasticity mechanisms of ultrasound neuromodulation

This paper develops a whole-brain model to study how transcranial ultrasound stimulation (TUS) induces functional changes in the brain, identifying two mechanisms that predict plasticity-driven effects.

Transcranial focused ultrasound stimulation of the anterior temporal lobe enhances semantic memory by modulating brain morphology, neurochemistry and neural dynamics

This study shows that transcranial ultrasound stimulation of the anterior temporal lobe improves semantic memory by altering brain structure, chemistry, and function.

Ventricle stimulation as a potential gold-standard control stimulation site for transcranial focused ultrasound stimulation

This paper evaluates ventricle-focused ultrasound stimulation as a control for transcranial FUS, finding it does not alter brain structure or function and is indistinguishable from sham stimulation.

Transcranial ultrasound stimulation effect in the redundant and synergistic networks consistent across macaques

This study examines how transcranial ultrasound stimulation affects neural networks in macaques, showing changes in specific brain networks and network topology.

OptDesign: Identifying Optimum Design Strategies in Strain Engineering for Biochemical Production

OptDesign identifies optimal strain design strategies for biochemical production in E. coli by combining regulation and knockout interventions using a two-step approach.

Dynamic reconfiguration of macaque brain networks during free-viewing of natural scenes

This study analyzes dynamic brain network reconfiguration in macaques during free-viewing of natural scenes, revealing functional and structural connectivity changes related to visual stimuli.

BioDynaMo: a general platform for scalable agent-based simulation

BioDynaMo is a scalable agent-based simulation platform that outperforms existing tools by three orders of magnitude, enabling large-scale simulations in neuroscience, oncology, and epidemiology.

Creative destruction: a basic computational model of cortical layer formation

The paper presents a computational model of cortical layer formation that incorporates apoptosis and gene regulatory dynamics to explain normal and pathological development.

Computational modelling of the long-term effects of brain stimulation on the local and global structural connectivity of epileptic patients

This study uses a computational model to simulate the long-term effects of brain stimulation on structural connectivity in epileptic patients, finding that stimulation impacts both stimulated and non-stimulated regions and correlates with surgery outcomes.

Dynamic functional connectivity changes in dementia with Lewy bodies and Alzheimer’s disease

This study examines dynamic functional connectivity in dementia with Lewy bodies and Alzheimer’s disease, finding reduced network efficiency variability in DLB but no significant clinical correlations.

The functional brain favours segregated modular connectivity at old age unless targeted by neurodegeneration

The paper examines how modular connectivity in the brain changes with age and neurodegeneration, finding increased segregation and variability in older adults and distinct pathological patterns in neurodegenerative diseases.