Maunick Lefin Koloko Ngassie

The paper shows that in IPF lungs, COL6 gene expression is higher but protein levels and synthesis around airways and vessels are lower, suggesting disrupted matrix organization and fibroblast persistence.

This study investigates the role of Piezo1/2 channels in airway smooth muscle cells of COPD patients, finding altered expression and function linked to ECM changes.

The paper identifies fibroblast-derived osteoglycin as a key factor promoting epithelial cell repair and presents its active fragment as a potential therapeutic for lung diseases.

The paper compares ECM protein expression in severe-early onset and moderate COPD to controls, identifying ECM signatures linked to disease severity and subtypes.

This study identifies seven age-associated ECM proteins with increased expression in human lung tissue and demonstrates age-related differences in specific lung compartments.