Author

David Carslake

University of BristolORCID 0000-0003-2916-4546Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

George Davey SmithiD· 3 shared Gibran HemaniiD· 2 shared Nicholas John TimpsoniD· 2 shared Anubha MahajaniD· 1 shared Ashley Budu‐AggreyiD· 1 shared Caroline J. BulliD· 1 shared Daniel John LawsoniD· 1 shared Eleanor C. M. SandersoniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersGenetics

George Davey SmithORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintDec 17, 2025

An Evaluation of Age-varying Genetic Effects underlying Body-mass Index and Blood Pressure in the UK Biobank

Genevieve M Leyden, Panagiota Pagoni, Grace Marion Power…·Eleanor C. M. Sanderson

This paper evaluates age-varying genetic effects on BMI and blood pressure traits using UK Biobank data, finding trait-dependent interactions that influence cardiovascular outcomes.

DOI 10.64898/2025.12.16.25342301

humanGWAS summary statistics

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GeneticsDiabetes CarePeer-reviewedApr 28, 2020

Early metabolic features of genetic liability to type 2 diabetes: cohort study with repeated metabolomics across early life

Joshua A. Bell, Caroline J. Bull, Marc James Gunter…·Emma E. Vincent

This study identifies early metabolic features associated with genetic liability to type 2 diabetes across childhood, adolescence, and young adulthood using longitudinal metabolomics data.

35 citations

humanmetabolomics

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GeneticsNature CommunicationsPeer-reviewedJan 18, 2019

Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.

Simon J. Haworth, Ruth E. Mitchell, Laura J. Corbin…·Nicholas John Timpson

The paper examines geographical stratification of genetic variants in UK Biobank data and its impact on genetic association analyses, finding that genetic risk scores show geographic structure and may introduce bias.

314 citationstop 1%

humanGWAS summary statistics

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