Ruth E. Mitchell

The paper identifies African-specific genetic loci associated with iron status and risk of severe malaria and bacteremia in children, highlighting limited transferability of European polygenic risk scores.

The paper identifies a novel genetic locus OSBPL11 associated with vitamin D levels and cardiometabolic health in African populations through genome-wide analysis.

This study performs a genome-wide association study for Long COVID, identifying a significant association with the FOXP4 locus and highlighting the role of pulmonary dysfunction and COVID-19 severity.

This study identifies 118 candidate causal genes and 21 novel lipid loci on the X chromosome through a multi-ancestry meta-analysis of blood lipid levels, revealing sex-biased effects and pleiotropy with cardiovascular and hormonal traits.

This paper integrates GWAS data with functional genomic datasets to identify regulatory mechanisms and causal genes underlying lipid-related traits.

This study imputed HMOX1 GT(n) repeat length in European cohorts and found no significant phenotypic associations despite high imputation accuracy.

This paper reviews statistical methods to detect and adjust for collider bias in genetic and Mendelian randomization studies of disease progression using individual and summary-level data.

The paper describes the continental ancestry and population structure of non-white British individuals in the UK Biobank using reference populations and clustering methods.

The paper uses multi-omics methods to identify genes and cell-type specific effects associated with autoimmune diseases and cancer outcomes.

This study uses Mendelian randomization to assess if smoking causally affects multiple sclerosis risk, finding no significant association.

The paper examines geographical stratification of genetic variants in UK Biobank data and its impact on genetic association analyses, finding that genetic risk scores show geographic structure and may introduce bias.