Author

Mary H. Young

Bristol-Myers Squibb (United States)ORCID 0000-0003-2921-6107Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander V. RatushnyiD· 1 shared Andrew DervaniD· 1 shared Anne-Renée Van der Vuurst de Vries· 1 shared Aye T. Chen· 1 shared Brian A. FoxiD· 1 shared Brian J. BelmontiD· 1 shared Bryce DainesiD· 1 shared Christopher Mark Hill· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Alexander V. RatushnyORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 10, 2023

Switching circuits: Modulating NK cell response to TGF-β using novel receptors

Rebekah Turk, Lan Shen Guo, Brian J. Belmont…·Max Darnell

This study identifies novel switch receptors for NK cells that enhance cytotoxicity and persistence in the presence of TGF-β through a pooled screening approach.

DOI 10.1101/2023.12.10.570687

humanexperimental assay

𝕏 PostBluesky

Systems BiologyScientific ReportsPeer-reviewedFeb 5, 2020

Integrative network modeling reveals mechanisms underlying T cell exhaustion

Hamid Bolouri, Mary H. Young, Joshua N. Beilke…·Alexander V. Ratushny

The paper uses network modeling to identify molecular mechanisms driving T cell exhaustion and validates predictions through experimental testing.

27 citations

humanbulk RNA-seq

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