Author

Andrew P. K. Wodrich

National Institutes of HealthORCID 0000-0003-2933-3389Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2

Frequent Co-Authors

Brent T. HarrisiD· 2 shared Edward GinigeriD· 2 shared

Activity by Year

2024-2024 · peak 2/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersNeuroscience

Brent T. HarrisORCID

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2 papers

Recent·Most cited

NeuroscienceBiology OpenPeer-reviewedJun 24, 2024

Changes in mitochondrial distribution occur at the axon initial segment in association with neurodegeneration in Drosophila

Andrew P. K. Wodrich, Brent T. Harris, Edward Giniger

The paper investigates mitochondrial distribution changes in Drosophila neurodegeneration, finding altered mitochondrial localization at the axon initial segment associated with reduced Cdk5 activity.

5 citations

Drosophilaexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 25, 2024

MANIPULATING MITOCHONDRIAL REACTIVE OXYGEN SPECIES ALTERS SURVIVAL IN UNEXPECTED WAYS IN A DROSOPHILA MODEL OF NEURODEGENERATION

Andrew P. K. Wodrich, Brent T. Harris, Edward Giniger

This study manipulates mitochondrial reactive oxygen species in a Drosophila neurodegeneration model and finds that increased H2O2 correlates with improved survival, while drug effects depend on treatment timing, duration, and genotype.

DOI 10.1101/2024.03.25.586603

Drosophilaexperimental assay

𝕏 PostBluesky