Edward Giniger

This study examines how nanotopography influences actin wave dynamics and neurite navigation in developing neurons, showing reduced responsiveness to physical cues as neurons mature.

The paper investigates mitochondrial distribution changes in Drosophila neurodegeneration, finding altered mitochondrial localization at the axon initial segment associated with reduced Cdk5 activity.

This study manipulates mitochondrial reactive oxygen species in a Drosophila neurodegeneration model and finds that increased H2O2 correlates with improved survival, while drug effects depend on treatment timing, duration, and genotype.

The paper investigates the role of Ena/VASP proteins in axon growth by analyzing filopodial morphology and actin organization in Drosophila neurons.

The paper shows that Abl kinase, regulated by Notch signaling, negatively controls ommatidial rotation in Drosophila by modulating adherens junction dynamics during eye development.

The paper shows HTT represses ABL activity, which is necessary for axonal growth in Drosophila mushroom bodies.

The paper shows that actomyosin contractility enhances Notch-mediated signaling and patterning in fly dorsal thorax development through basal protrusions.