Gokul M. Das

This paper shows that Tamoxifen and Doxorubicin together target the ER beta-mutant p53-p73 axis in TNBC, enhancing cell death through apoptosis and ferroptosis.

This paper identifies AADAT as a metabolic immune checkpoint in TNBC that promotes immune evasion by regulating malate and CoQ10, and shows that malate supplementation can reverse immunotherapy resistance.

This study uses spatial omics to identify distinct tumor microenvironment profiles in Black and White American TNBC patients, linking them to different immunosuppressive mechanisms and clinical outcomes.