Molecular BiologybioRxivPreprint
Altering rRNA 2'O-methylation pattern during neuronal differentiation is regulated by FMRP
Michelle Ninochka D’Souza, Naveen Kumar Chandappa Gowda, Nivedita Hariharan…·Ravi Sondekoppa Muddashetty
This study shows that FMRP regulates the 2O-methylation pattern of rRNA during neuronal differentiation, which affects protein synthesis and is disrupted in Fragile X Syndrome.
DOI 10.1101/2024.07.25.605157