Author

Zhen Gu

University of California, Los AngelesORCID 0000-0003-2947-4456Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Aaron Zhang· 1 shared Amy C. RowatiD· 1 shared Chuhuan Jiang· 1 shared Dongping QiiD· 1 shared Guangzheng Xu· 1 shared Hui ZhangiD· 1 shared Jennifer SotoiD· 1 shared Jian Yao· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Aaron Zhang

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 12, 2025

An ultra-long acting insulin enables glucose-synchronised release

Yang Zhang, Juan Zhang, Kangfan Ji…·Zhen Gu

This paper develops a glucose-responsive insulin analogue with ultra-long duration and glucose-synchronised release, showing prolonged normoglycaemia in diabetic mice and minipigs.

2 citations

mousehuman

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Cell BiologyNature CommunicationsPeer-reviewedApr 30, 2025

Viscoelastic Extracellular Matrix Enhances Epigenetic Remodeling and Cellular Plasticity

Yifan Wu, Yang Song, Jennifer Soto…·Song Li

This study shows viscoelastic substrates enhance epigenetic remodeling and cellular plasticity in fibroblasts, improving reprogramming efficiency into neurons and pluripotent stem cells.

68 citationstop 1%

humanATAC-seq

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