Author

Dennis M. Joshy

University of California, Santa BarbaraORCID 0000-0003-2966-257XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Aqib HasnainiD· 1 shared Enoch YeungiD· 1 shared Jen Smith· 1 shared Shara Balakrishnan· 1 shared Soojin V. YiiD· 1 shared Steven B. HaaseiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 10 mutual co-author links

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1 shared paperSynthetic Biology

Aqib HasnainORCID

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2 papers

Recent·Most cited

NeuroscienceDOAJ (DOAJ: Directory of Open Access Journals)Peer-reviewedMay 1, 2026

Expanding canonical cortical cell type markers in the era of single-cell transcriptomics

Dennis M. Joshy, Soojin V. Yi

The paper quantifies marker fidelity and background expression of cortical cell types using single-nucleus transcriptomics data and extends canonical markers with improved subtype-specific markers.

DOI 10.1038/s41598-026-51501-2

humanscRNA-seq

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Synthetic BiologybioRxivPreprintMay 27, 2022

Learning perturbation-inducible cell states of novel compounds from observability analysis of transcriptome dynamics

Aqib Hasnain, Shara Balakrishnan, Dennis M. Joshy…·Enoch Yeung

The paper develops a machine learning approach to identify perturbation-inducible genes from time-series RNA-seq data, applying it to discover malathion-responsive promoters in Pseudomonas fluorescens.

1 citation

bacteria (other)bulk RNA-seq

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